Preclinical screening of phyllanthus amarus ethanolic extract for its analgesic and antimicrobial activity

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چکیده

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Analgesic activity of aqueous leaf extract of Phyllanthus amarus.

Various doses of the aqueous extract of Phyllanthus amarus (AEPA) were investigated for analgesic and anti-inflammatory activities using both thermal and chemical models of pain assessment in rats. The extract caused a significant (P < 0.05) dose related increase inhibition of the carrageenan-induced paw oedema in the rats. The inhibition produced by 200 mg/kg AEPA (70.20%) was significantly hi...

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antioxidant and antimicrobial activity of allium jesdianum extract

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Hypoglycemic activity of ethanolic leaf extract of Phyllanthus amarus in alloxan induced diabetic mice

Phyllanthus amarus is an indigenous medicinal plant, with a folk reputation as hypoglycemic agent in Central and Southern India. In the present investigation hypoglycemic activity of ethanolic leaf extract of Phyllanthus amarus was evaluated using alloxan induced hyperglycemic mice. Blood glucose levels of all the mice of each group were tested before the treatments on fasting mice and then tes...

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Antidiabetic effect of ethanolic leaf extract of Phyllanthus amarus in alloxan induced diabetic mice

Phyllanthus amarus Schum. Thonn. is an indigenous medicinal plant, which has a folk reputation in central and southern India as hypoglycemic agent. The present investigation was carried out to evaluate the antidiabetic effect of ethanolic leaf extract of Phyllanthus amarus in alloxan induced diabetic mice. Blood glucose levels and body weights of control and diabetic mice were monitored. In the...

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Analgesic Activity of Phyllanthus lawii Extract in Swiss Albino Mice

The analgesic activity of the methanol extract of Phyllanthus lawii (MEPL) was investigated in Swiss albino mice with hot plate and acetic acid induced writhing models. The results suggested that MEPL possess potent analgesic activity. The MEPL produced a significant decrease in mice writhing induced by acetic acid suggesting peripheral analgesic activity and elevated mean basal reaction time i...

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ژورنال

عنوان ژورنال: Pharmacognosy Research

سال: 2015

ISSN: 0974-8490

DOI: 10.4103/0974-8490.159577